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dc.contributor.authorDespriee, Åshild
dc.contributor.authorSmåstuen, Milada Cvancarova
dc.contributor.authorGlavin, Kari
dc.contributor.authorCarlsen, Karin Cecilie Lødrup
dc.contributor.authorMagi, Caroline Aleksi Olsson
dc.contributor.authorSöderhäll, Cilla
dc.contributor.authorHedlin, Gunilla
dc.contributor.authorNordhagen, Live Solveig
dc.contributor.authorJonassen, Christine M
dc.contributor.authorRehbinder, Eva Maria
dc.contributor.authorNordlund, Bjørn Kristian
dc.contributor.authorSkjerven, Håvard Ove
dc.identifier.citationJournal of Clinical Nursing (JCN). 2023, 32 (19-20), 7605-7617.en_US
dc.descriptionThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en_US
dc.description.abstractAims and Objectives: The primary aim was to explore whether infants with pain symptoms (colic, abdominal pain and visit to healthcare provider with pain or other discomforts) had increased multimorbidity (common infections, eczema and food sensitivity) compared with infants without these conditions. Secondarily, we aimed to determine whether infant pain symptoms were associated with maternal perceived stress in pregnancy and 3 months postpartum. Background: Infant colic and abdominal pain are common concerns in early infancy. Nevertheless, to our knowledge, little research exists on the relationship between infant pain and common infant infections, eczema and food sensitization as comorbidities, and the impact of infant pain on the development of maternal perceived stress from pregnancy to infancy is inconsistent. Design: This study was cross-sectional and partly prospective. Methods: The sample consisted of mother–infant pairs (N = 1852); information regarding infant pain and multimorbidity was collected from the 3-month questionnaire and postpartum visits in the PreventADALL prospective cohort study. Chi-square tests and regression analyses were conducted. The STROBE checklist was followed. Results: Our results showed a statistically significant higher proportion of respiratory and other infections in infants with pain symptoms. The odds of infant pain were higher for infants with multimorbidity compared to those with no comorbidity. Mothers of infants with colic and of infants visiting healthcare with pain and other discomforts reported statistically significant higher perceived stress by 3 months compared with mothers of infants with no reported pain. Conclusion: Our results indicate an association between infant pain symptoms and the presence of infections. Mothers of infants with colic and visiting healthcare had higher perceived stress compared to the no pain group. Implications for Practice: Our study indicates that infant pain is associated with infant multimorbidity and maternal perceived stress, which may be useful when planning diagnostic, treatment and coping strategies in infant and family care. Patient or Public Contribution: The PreventADALL is a collaborative study with governmental and patient organisation representation. Selected infants with parents were also contributing during calibrating courses on eczema assessment for the data collectors. Trial Registration: The study was approved by the Regional Committee in Norway (2014/518) and Sweden (2014/2242–31/4) and registered at (NCT02449850). Link for clinical trials:
dc.publisherJohn Wiley & Sonsen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internasjonal*
dc.subjectmaternal stressen_US
dc.subjectabdominal painen_US
dc.titleInfant colic and abdominal pain; associations with infant multimorbidity and maternal perceived stress up to 3 months postpartum—A cross-sectional/cohort study in the PreventADALL studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.rights.holder© 2023 The Authors. Journal of Clinical Nursing published by John Wiley & Sons Ltden_US
dc.source.journalJournal of Clinical Nursing (JCN)en_US

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Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internasjonal