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dc.contributor.authorHjelmeland, Inger Helen Hardeland
dc.contributor.authorDrageset, Jorunn
dc.contributor.authorNordvik, Øyvind
dc.contributor.authorBeisland, Elisabeth Grov
dc.identifier.citationHealth and Quality of Life Outcomes.2022, 20, Article number: 154, 1-11en_US
dc.descriptionThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit The Creative Commons Public Domain Dedication waiver (http://creativeco applies to the data made available in this article, unless otherwise stated in a credit line to the dataen_US
dc.description.abstractObjective: Quality of Life (QoL) in elderly cancer patients is a topic that has been little explored. This systematic review aims to identify, assess, and report the literature on QoL in home-dwelling cancer patients aged 80 years and older and what QoL instruments have been used. Methods: We systematically searched the databases of Medline, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), PsykINFO, Scopus, Epistemonikos and Cinahl to identify studies of any design measuring QoL among home-dwelling cancer patients aged 80 years and older. We screened the titles and abstracts according to a predefned set of inclusion criteria. Data were systematically extracted into a predesigned data charting form, and descriptively analyzed. The included studies were assessed according to the Critical Appraisal Skills Programme (CASP) checklists, and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement (PRISMA) checklist was used to ensure rigor in conducting our investigations and reporting our fndings. This systematic review was registered in PROSPERO (CRD42021240170). Results: We included three studies that specifcally analyze QoL outcomes in the subgroup of home-dwelling cancer patients aged 80 years and older, with a total of 833 participants having various cancer diagnoses. 193 of the participants included in these three studies were aged 80 years or more. Diferent generic and cancer-specifc QoL instruments as well as diferent aims and outcomes were studied. All three studies used a diagnosis-specifc instrument, but none of them used an age-specifc instrument. Despite heterogeneity in cancer diagnoses, instruments used, and outcomes studied, QoL in home-dwelling cancer patients aged over 80 years old seems to be correlated with age, physical function, comorbidity, living alone, needing at-home care services, being in a poor fnancial situation and having a small social network. Conclusion: Our systematic review revealed only three studies exploring QoL and its determinants in the specifc subgroup of home-dwelling cancer patients aged 80 years and over. A gap in the knowledge base has been identifed. Future studies of this increasingly important and challenging patient group must be emphasized. Subgroup analyses by age must be performed, and valid age and diagnosis specifc QoL instruments must be used to generate evidence in this segment of the population.en_US
dc.publisherBioMed Central (BMC)en_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.subjectsystematic reviewen_US
dc.subjecthome-dwelling cancer patientsen_US
dc.subject80 years and olderen_US
dc.subjectquality of lifeen_US
dc.titleQuality of life in home-dwelling cancer patients aged 80 years and older: a systematic reviewen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.rights.holder© The Author(s) 2022en_US
dc.source.journalHealth and Quality of Life Outcomesen_US

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